🩺 Paracetamol: Complete Medical Guide
Introduction
Paracetamol (Acetaminophen) is one of the most widely used medicines for relieving pain and fever. It is trusted worldwide for its effectiveness and safety when taken in proper doses.
What is Paracetamol?
- Generic Name: Paracetamol
- Other Name: Acetaminophen
- Drug Class: Analgesic & Antipyretic
- Forms Available: Tablet, Syrup, Drops, Injection, Suppository
Uses of Paracetamol
Paracetamol is used for:
- Fever
- Headache
- Toothache
- Muscle pain
- Back pain
- Joint pain
- Menstrual cramps
- Post-surgical pain
- Cold & flu symptoms
Mechanism of Action
Paracetamol works mainly in the central nervous system:
- Inhibits the Cyclooxygenase (COX) enzyme in the brain
- Reduces production of Prostaglandins (pain & fever mediators)
- Acts on the hypothalamus to lower body temperature
Unlike NSAIDs, paracetamol has minimal anti-inflammatory effect.
Dosage
Adults
- 500–1000 mg every 6–8 hours
- Maximum: 4000 mg/day
Children
- 10–15 mg/kg per dose
- Every 6–8 hours
- Maximum 4 doses/day
Infants
Dose strictly as prescribed by doctor.
Side Effects
Common:
- Nausea
- Vomiting
- Skin rash
- Headache
Serious (Overdose):
- Liver damage
- Jaundice
- Abdominal pain
- Liver failure
Precautions
- Do not exceed recommended dose
- Avoid alcohol
- Use carefully in liver disease
- Check combination cold medicines
Contraindications
Avoid in:
- Severe liver disease
- Chronic alcoholism
- Allergy to paracetamol
Drug Interactions
Interacts with:
- Alcohol
- Warfarin
- Anti-epileptic drugs
- Rifampicin
Use in Pregnancy & Breastfeeding
Paracetamol is considered safe when used in proper doses.
Overdose & Treatment
Symptoms: nausea, vomiting, sweating, confusion
Treatment: Immediate medical care
Antidote: N-Acetylcysteine (NAC)
❓ Frequently Asked Questions (FAQ)
Is paracetamol safe for daily use?
Yes, when used within recommended limits.
Can I take paracetamol with antibiotics?
Yes, generally safe.
Is paracetamol better than ibuprofen?
For pain & fever, yes. For inflammation, ibuprofen may be better.
Can paracetamol damage the liver?
Yes, in overdose or long-term excessive use.
Is paracetamol safe for children?
Yes, with proper dosing.
⚠️ Medical Disclaimer (For DrugInfoCare.com)
The information provided on DrugInfoCare.com is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or qualified healthcare provider before taking any medication. Never ignore professional medical advice because of something you have read on this website.
